Conserved Site

4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site (IPR018294)

Short name: ISPD_synthase_CS

Description

4-diphosphocytidyl-2C-methyl-D-erythritol synthase, a bacterial ispD protein, catalyzes the third step of the deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate [PMID: 10841550]. The isoprenoid pathway is a well known target for anti-infective drug development [PMID: 17081012, PMID: 17921290].

This entry represents a pattern that identifies IspD. The pattern is centred on a central conserved region that contains a conserved Asp and Arg residues.

GO terms

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns