Conserved Site

Peptidyl-tRNA hydrolase, conserved site (IPR018171)

Short name: Pept_tRNA_hydro_CS


Peptidyl-tRNA hydrolase (EC: (PTH) is a bacterial enzyme that cleaves peptidyl-tRNA or N-acyl-aminoacyl-tRNA to yield free peptides or N-acyl-amino acids and tRNA. The natural substrate for this enzyme may be peptidyl-tRNA which drop off the ribosome during protein synthesis [PMID: 1833189, PMID: 8635758]. Bacterial PTH has been found to be evolutionary related to a yeast protein [PMID: 8563640].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004045 aminoacyl-tRNA hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns