Active Site

Glycoside hydrolase, family 32, active site (IPR018053)

Short name: Glyco_hydro_32_AS


It has been shown [PMID: 1747104, PMID: 2254250] that the following glycosyl hydrolases can be classified into a single family on the basis of sequence similarities:

  • Inulinase (EC: (or inulase) from the fungi Kluyveromyces marxianus (Yeast) (Candida kefyr).
  • Beta-fructofuranosidase (EC:, commonly known as invertase in fungi and plants and as sucrase in bacteria (gene sacA or scrB).
  • Raffinose invertase (EC: (gene rafD) from Escherichia coli raffinose plasmid pRSD2.
  • Levanase (EC: (gene sacC) from Bacillus subtilis.

One of the conserved regions in these enzymes is located in the N-terminal section and contains an aspartic acid residue which has been shown, in yeast invertase to be important for the catalytic mechanism [PMID: 2113524].

GO terms

Biological Process

GO:0005975 carbohydrate metabolic process

Molecular Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns