Cysteine desulfurase NifS, bacterial/archaeal (IPR017772)

Short name: Cys_deSase_NifS_bac/arc

Overlapping homologous superfamilies

Family relationships


This entry represents NifS, one of several related families of cysteine desulfurase involved in iron-sulphur (FeS) cluster biosynthesis. NifS is part of the NIF (nitrogen fixation) system, and is usually encoded with other nif genes involved in nitrogenase expression and nitrogen fixation. These proteins include a clade nearly always found in extended nitrogen fixation genomic regions, plus a second clade more closely related to the first than to IscS and also part of NifS-like/NifU-like systems. This entry does not cover a more distant clade found in the epsilon proteobacteria such as Helicobacter pylori, also named NifS in the literature. This clade is covered instead by IPR017773.

GO terms

Biological Process

GO:0006520 cellular amino acid metabolic process

Molecular Function

GO:0031071 cysteine desulfurase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.