LOB domain-containing protein (IPR017414)

Short name: LOBD

Overlapping homologous superfamilies


Family relationships



This entry contains a subset of the AS2/LOB (ASYMMETRIC LEAVES 2/LATERAL ORGAN BOUNDARIES) gene family that are highly homologous and plant specific.

The N terminus contains a conserved approximately 100-amino acid domain (the LOB domain) that is present in A. thaliana proteins and in proteins from a variety of other plant species. Genes encoding LOB domain (LBD) proteins are expressed in a variety of temporal- and tissue-specific patterns, suggesting that they may function in diverse processes [PMID: 12068116, PMID: 19154202]. The LOB domain contains conserved blocks of amino acids that identify the LBD gene family. In particular, a conserved C-x(2)-C-x(6)-C-x(3)-C motif, which is defining feature of the LOB domain, is present in all LBD proteins. It is possible that this motif forms a new zinc finger [PMID: 12068116].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.