Homologous Superfamily

DNA-binding domain superfamily (IPR016177)

Short name: DNA-bd_dom_sf

Overlapping entries


This superfamily represents a DNA-binding domain with a 2-layer beta(3)-alpha fold that is found in several DNA-binding proteins, including:

  • DNA-binding domain of tn916 integrase [PMID: 9665166].
  • N-terminal DNA-binding domain of lambda integrase [PMID: 15973401].
  • GCC-box DNA-binding domains of certain transcription factors [PMID: 9736626].
  • Methyl-CpG DNA-binding domain found in Methyl-CpG-binding protein 2 (MECP2) [PMID: 10518942] and methylation-dependent transcriptional repressor MBD1/PCM1 [PMID: 11371345].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003677 DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.