Homologous Superfamily

Prismane-like, alpha/beta-sandwich (IPR016099)

Short name: Prismane-like_a/b-sand

Overlapping entries


Prismane (hybrid-cluster) proteins are present in a wide range of bacteria and archaea, and are characterised by their two Fe/S centres: a [4Fe-4S] cubane cluster, and a hybrid [4Fe-2S-2O] cluster [PMID: 10651802]. Prismane proteins contain four domains: two spectrin repeat-like 3-helical bundle domains, and two alpha/beta domains with Rossmann-fold topology. Several proteins are structurally related to Prismane, including Ni-containing carbon monoxide dehydrogenase (CODH) (lack one of the N-terminal 3-helical bundle domains), the alpha and beta subunits of bifunctional CODH, and the alpha and beta subunits of acetyl-CoA synthetase.

This entry represents the 3-layer (alpha/beta/alpha) sandwich domain found in prismane, CODH, and in acetyl-CoA synthases.

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.