InterPro-
Overview
-
Cross-references
WD40/YVTN repeat-like-containing domain superfamily (IPR015943)
Short name: WD40/YVTN_repeat-like_dom_sf
Overlapping entries
- Sema domain (IPR001627)
- G-protein, beta subunit (IPR001632)
- WD40 repeat (IPR001680)
- HELP (IPR005108)
- Amine dehydrogenase heavy chain (IPR009451)
- Nitrous oxide reductase, N-terminal (IPR011045)
- Two component regulator propeller (IPR011110)
- Streptogramin lyase (IPR011217)
- YVTN beta-propeller repeat (IPR011964)
- Methylamine dehydrogenase heavy chain (IPR013476)
- Domain of unknown function DUF1899 (IPR015048)
- Coronin (IPR015505)
- Semaphorin 4F (IPR015512)
- Semaphorin 3E (IPR015513)
- Semaphorin 6C (IPR015514)
- Guanine nucleotide-binding protein, beta subunit (IPR016346)
- Photosynthesis system II assembly factor Ycf48/Hcf136 (IPR016705)
- Apoptotic protease-activating factor 1 (IPR017251)
- Dynein regulator LIS1 (IPR017252)
- Actin-related protein 2/3 complex subunit 1 (IPR017383)
- WD repeat protein DCAF11/LEC14B (IPR017399)
- WD repeat protein 55 (IPR017422)
- Outer membrane protein assembly factor BamB (IPR017687)
- Lactonase, 7-bladed beta propeller (IPR019405)
- Domain of unknown function DUF2415 (IPR019417)
- WD40 repeat, conserved site (IPR019775)
- G-protein beta WD-40 repeat (IPR020472)
- Histone-binding protein RBBP4, N-terminal (IPR022052)
- PQQ-dependent catabolism-associated beta-propeller protein (IPR022456)
- 6-phosphogluconolactonase, YbhE-type (IPR022528)
- Nitrous-oxide reductase (IPR023644)
- Quinohemoprotein amine dehydrogenase, beta subunit (IPR023879)
- Nitrous-oxide reductase, Sec-dependent (IPR026468)
- U4/U6 small nuclear ribonucleoprotein Prp4 (IPR027106)
- Semaphorin (IPR027231)
- Coronin 1C (IPR027333)
- Coronin 2A (IPR027335)
- Coronin 6 (IPR027337)
- Coronin 2B (IPR027339)
- Coronin 1B (IPR027340)
- Eukaryotic translation initiation factor 3 subunit I (IPR027525)
- Oligogalacturonate lyase domain (IPR027946)
- Photosynthesis system II assembly factor Ycf48/Hcf136-like domain (IPR028203)
- WD repeat WDR12/Ytm1 (IPR028599)
- Coronin 1A (IPR029508)
- Actin-related protein 2/3 complex subunit 1A (IPR030140)
- Actin-related protein 2/3 complex subunit 1B (IPR030141)
- Protein of unknown function DUF5074 (IPR031815)
- Partner and localiser of BRCA2, WD40 domain (IPR031920)
- Enhancer of mRNA-decapping protein 4, WD40 repeat region (IPR032401)
- Pre-mRNA-processing factor 17 (IPR032847)
- WD repeat domain phosphoinositide-interacting protein 1 (IPR032909)
- WD repeat domain phosphoinositide-interacting protein 2 (IPR032911)
- The WD repeat Cdc20/Fizzy family (IPR033010)
- Cilia- and flagella-associated protein 52 (IPR033015)
- Cmr1/WDR76 (IPR033052)
- Cell division cycle protein 20 homologue (IPR033187)
- DNA damage-binding protein 2 (IPR033312)
- Sema domain superfamily (IPR036352)
- Polycomb protein EED (IPR037352)
- Sec13/Seh1 family (IPR037363)
- Target of rapamycin complex subunit LST8 (IPR037588)
- Protein Sec13 (IPR037596)
- Nucleoporin Nup37 (IPR037626)
- mRNA export factor Gle2/RAE1 (IPR037631)
- WD repeat-containing protein 5 (IPR037834)
- WD repeat-containing protein 82 (IPR037846)
- Retinoblastoma-binding protein 5/Swd1 (IPR037850)
- COMPASS component Swd2 (IPR037867)
- Pre-mRNA-processing factor 19 (IPR038959)
- Ribosomal RNA-processing protein Rrp9-like (IPR039241)
- RON, Sema domain (IPR039413)
- Nucleoporin Nup159/Nup146, N-terminal (IPR039462)
- WD repeat-containing protein WDR46/Utp7 (IPR040315)
- EARP and GARP complex-interacting protein 1 (IPR040323)
Description
This superfamily represents a WD40/YVTN repeat-like domain. Both the WD40 and the YVTN repeated motifs consist of about 40 residues, and although they consist of distinct sequences, they do share a similar structure. Structurally, both the WD40 and the YVTN repeated motifs form seven-bladed propellers (although some members can contain eight blades), which consist of seven 4-stranded beta-sheets.
The WD40-type repeat domain is found in the beta-1 subunit of the signal-transducing G protein [PMID: 10360181], in yeast Tup1 protein [PMID: 10856245], in Groucho [PMID: 12057191], in the yeast cell cycle protein Cdc4 [PMID: 12553912] and in actin-interacting protein 1 [PMID: 15150269].
The YVTN-type repeat domain is found in archaeal surface layer proteins (SLPs) that protect cells from extreme environments [PMID: 12377130], in quinohemoprotein amine dehydrogenase (QHNDH) [PMID: 12925784], and in methylamine dehydrogenase [PMID: 9514722].
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0005515 protein binding
Cellular Component
No terms assigned in this category.
Contributing signatures
- G3DSA:2.130.10.10 (G3DSA:2.130.10.10)
