Homologous Superfamily

Lipid transport protein, beta-sheet shell (IPR015819)

Short name: Lipid_transp_b-sht_shell

Overlapping entries


This superfamily represents beta-sheet shell domains found in lipid transport proteins such as vitellinogen. Vitellinogen precursors provide the major egg yolk proteins that are a source of nutrients during early development of oviparous vertebrates and invertebrates. Vitellinogen precursors are multi-domain apolipoproteins that are cleaved into distinct yolk proteins. Different vitellinogen precursors exist, which are composed of variable combinations of yolk protein components; however, the cleavage sites are conserved. In vertebrates, a complete vitellinogen is composed of an N-terminal signal peptide for export, followed by four regions that can be cleaved into yolk proteins: lipovitellin-1, phosvitin, lipovitellin-2, and a von Willebrand factor type D domain (YGP40) [PMID: 17314313, PMID: 12135361]. Domains with a beta-sheet shell topology can be found within both lipovitellin-1 and lipoviteliin-2 peptide products.

GO terms

Biological Process

GO:0006869 lipid transport

Molecular Function

GO:0005319 lipid transporter activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.