Proline oxidase family (IPR015659)

Short name: Proline_oxidase

Overlapping homologous superfamilies

Family relationships



This entry includes a group of proline dehydrogenases (proline oxidases) found in bacteria, archaea and eukaryotes (mitochondria).

This entry includes FadM from Bacillus subtilis subsp. natto [PMID: 17536821] and slgA from Drosophila melanogaster. They convert proline to delta-1-pyrroline-5-carboxylate [PMID: 8096642]. This entry also includes mammalian hydroxyproline dehydrogenase which converts trans-4-L-hydroxyproline to delta-1-pyrroline-3-hydroxy-5-carboxylate [PMID: 25697095].

GO terms

Biological Process

GO:0006562 proline catabolic process

Molecular Function

GO:0004657 proline dehydrogenase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.