Acetaldehyde dehydrogenase, C-terminal (IPR015426)

Short name: Acetylaldehyde_DH_C

Overlapping homologous superfamilies


Domain relationships



This C-terminal domain is found in prokaryotic acetaldehyde dehydrogenases, it adopts a structure consisting of an alpha-beta-alpha-beta(3) core, which mediates dimerisation of the protein [PMID: 12764229].

The acetaldehyde dehydrogenase family of bacterial enzymes catalyses the formation of acetyl-CoA from acetaldehyde in the 3-hydroxyphenylpropinoate degradation pathway. It occurs as a late step in the meta-cleavage pathways of a variety of compounds, including catechol, biphenyl, toluene, salicylate [PMID: 1732207].

GO terms

Biological Process

GO:0019439 aromatic compound catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0008774 acetaldehyde dehydrogenase (acetylating) activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.