Beta-trefoil DNA-binding domain (IPR015350)

Short name: Beta-trefoil_DNA-bd_dom

Overlapping homologous superfamilies

Domain relationships



This DNA-binding domain adopts a beta-trefoil fold, that is, a capped beta-barrel with internal pseudo threefold symmetry. In the DNA-binding protein LAG-1, it also is the site of mutually exclusive interactions with NotchIC (and the viral protein EBNA2) and corepressors (SMRT/N-Cor and CIR) [PMID: 15297877].

GO terms

Biological Process

GO:0006357 regulation of transcription by RNA polymerase II

Molecular Function

GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.