Family

Genome polyprotein, Flavivirus (IPR014412)

Short name: Gen_Poly_FLV

Overlapping homologous superfamilies

Family relationships

None.

Description

This group represents a genome polyprotein from Flavivirus. The polyprotein is cleaved by peptidases (including the NS3 protein, a serine endopeptidase [PMID: 17052977]) into 14 chains, including the RNA-directed RNA polymerase NS5 or non-structural protein 5, with three activities: mRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.56), mRNA (nucleoside-2'-O-)-methyltransferase (EC:2.1.1.57) and RNA-directed RNA polymerase (EC:2.7.7.48).

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003968 RNA-directed 5'-3' RNA polymerase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0004482 mRNA (guanine-N7-)-methyltransferase activity
GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0004252 serine-type endopeptidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF