Cytochrome c oxidase, subunit II (IPR014222)

Short name: Cyt_c_oxidase_su2

Overlapping homologous superfamilies

Domain relationships



This entry contains subunit II (CoxB) of cytochrome c oxidase. Cytochrome c oxidase is the terminal electron acceptor of mitochondria (and one of several possible acceptors in prokaryotes) in the electron transport chain of aerobic respiration. The enzyme couples the oxidation of reduced cytochrome c to the reduction of molecular oxygen to water. This process results in the pumping of four protons across the membrane that are used in the proton gradient powered synthesis of ATP. The oxidase contains two haem A cofactors and three copper atoms as well as other bound ions [PMID: 9380672].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.