Domain

Transcription factor PAP1 (IPR013910)

Short name: TF_PAP1

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

The transcription factor Pap1 regulates antioxidant-gene transcription in response to H2O2 [PMID: 15956211]. This region is cysteine rich. Alkylation of cysteine residues following treatment with a cysteine alkylating agent can mask the accessibility of the nuclear exporter Crm1, triggering nuclear accumulation and Pap1 dependent transcriptional expression [PMID: 12100563].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam