HicA mRNA interferase family (IPR012933)

Short name: HicA_mRNA_interferase

Overlapping homologous superfamilies

Family relationships



This entry represents the HicA mRNA interferase family, which form the toxic component of a toxin-antitoxin (TA) module [PMID: 16895922, PMID: 19060138]. Family members contain a double-stranded RNA-binding domain and probably act as translation-independent mRNA interferases. They may form a complex with the antitoxin HicB which inhibits their mRNA interferase activity [PMID: 16895922].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003729 mRNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.