Acetyl-CoA C-acyltransferase FadI (IPR012806)

Short name: Ac-CoA_C-AcTrfase_FadI

Overlapping homologous superfamilies

Family relationships

  • Thiolase (IPR002155)
    • Acetyl-CoA C-acyltransferase FadI (IPR012806)


This subunit of the FadJI complex has acetyl-CoA C-acyltransferase (EC: activity, and is also known as beta-ketothiolase and fatty oxidation complex, beta subunit, and YfcY. This protein is almost always located adjacent to FadJ (IPR012802). The FadJI complex is needed for anaerobic beta-oxidation of short-chain fatty acids in Escherichia coli.

GO terms

Biological Process

GO:0006631 fatty acid metabolic process
GO:0016042 lipid catabolic process

Molecular Function

GO:0003988 acetyl-CoA C-acyltransferase activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.