Acetyl-CoA C-acyltransferase FadA (IPR012805)

Short name: FadA

Overlapping homologous superfamilies

Family relationships

  • Thiolase (IPR002155)
    • Acetyl-CoA C-acyltransferase FadA (IPR012805)


This subunit of the FadBA complex has acetyl-CoA C-acyltransferase (EC: activity, and is also known as beta-ketothiolase and fatty oxidation complex, beta subunit. This protein is almost always located adjacent to FadB (IPR012799). The FadBA complex is the major complex active for beta-oxidation of fatty acids in Escherichia coli.

GO terms

Biological Process

GO:0006631 fatty acid metabolic process
GO:0016042 lipid catabolic process

Molecular Function

GO:0003988 acetyl-CoA C-acyltransferase activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.