Huwentoxin-II family (IPR012625)

Short name: Toxin_20

Overlapping homologous superfamilies


Family relationships



This entry consists of the huwentoxin-II (HWTX-II) family of toxins secreted by spiders. These toxins are found in venom that secreted from the bird spider Selenocosmia huwena Wang. The HWTX-II adopts a novel scaffold different from the ICK motif that is found in other huwentoxins. HWTX-II consists of 37 amino acids residues including six cysteines involved in three disulphide bridges [PMID: 15066414].

GO terms

Biological Process

GO:0009405 pathogenesis

Molecular Function

GO:0090729 toxin activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns