Family

dCTP deaminase (IPR011962)

Short name: dCTP_deaminase

Overlapping homologous superfamilies

Family relationships

None.

Description

Deoxycytidine triphosphate deaminase (dCTP deaminase) is an enzyme involved in nucleotide metabolism. It catalyses the formation of dUTP (deoxyuridine (5'-)triphosphate), which in turn is degraded by dUTPase (dUTP diphosphatase) to produce dUMP (deoxyuridine monophosphate). dUMP is the immediate precursor of thymidine nucleotides [PMID: 1324907].

Members of this family include the Escherichia coli monofunctional deoxycytidine triphosphate deaminase (dCTP deaminase) [PMID: 1324907] and a Methanocaldococcus jannaschii (Methanococcus jannaschii) bifunctional dCTP deaminase (EC:3.5.4.13)/dUTP diphosphatase (EC:3.6.1.23) [PMID: 12538648].

GO terms

Biological Process

GO:0006229 dUTP biosynthetic process

Molecular Function

GO:0008829 dCTP deaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
HAMAP