Domain

Domain of unknown function DUF1232 (IPR010652)

Short name: DUF1232

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This domain can be found in RNF170 from eukaryotes and some uncharacterised proteins from bacteria and archaea. RNF170 is an E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway [PMID: 21610068].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam