Homologous Superfamily

Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (IPR009014)

Short name: Transketo_C/PFOR_II

Overlapping entries


Transketolase C-terminal-like domains [PMID: 8176731] can be found in a number of different enzymes, including the C-terminal domain of the pyruvate dehydrogenase E1 component [PMID: 11955070], the C-terminal domain of branched-chain alpha-keto acid dehydrogenases [PMID: 10426958], and domain II of pyruvate-ferredoxin oxidoreductase (PFOR) [PMID: 11752578]. Structural studies reveal this domain to comprise of three layers alpha/beta/alpha. The mixed beta sheet consists of five strands in the order 13245, where strand 1 is antiparallel to the others. This domain has been proposed as a regulatory molecule binding site in transketolase [PMID: 1628611].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.