BFD-like [2Fe-2S]-binding domain (IPR007419)

Short name: BFD-like_2Fe2S-bd_dom

Overlapping homologous superfamilies


Domain relationships



The two Fe ions are each coordinated by two conserved cysteine residues. This domain occurs alone in small proteins such as bacterioferritin-associated ferredoxin (BFD, P13655). The function of BFD is not known, but it may be a general redox and/or regulatory component involved in the iron storage or mobilisation functions of bacterioferritin in bacteria [PMID: 8639572]. This domain is also found in nitrate reductase proteins in association with the nitrite and sulphite reductase 4Fe-4S domain (IPR006067), nitrite/sulphite reductase ferredoxin-like half domain (IPR005117). It is also found in NifU nitrogen fixation proteins, in association with NifU-like N-terminal domain (IPR002871) and C-terminal domain (IPR001075).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.