Pectinesterase inhibitor domain (IPR006501)

Short name: Pectinesterase_inhib_dom

Overlapping homologous superfamilies

Domain relationships



This domain inhibits pectin methylesterases (PMEs) and invertases through formation of a non-covalent 1:1 complex [PMID: 8521860]. It has been implicated in the regulation of fruit development, carbohydrate metabolism and cell wall extension [PMID: 10880981]. It may also be involved in inhibiting microbial pathogen PMEs. It has been observed that it is often expressed as a large inactive preprotein [PMID: 8521860]. It is also found at the N-termini of PMEs, suggesting that both PMEs and their inhibitor are expressed as a single polyprotein and subsequently processed. It has two disulphide bridges and is mainly alpha-helical [PMID: 10880981].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004857 enzyme inhibitor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.