Glutamate synthase, NADH/NADPH, small subunit 1 (IPR006005)

Short name: Glut_synth_ssu1

Overlapping homologous superfamilies


Family relationships



One pathway for the assimilation of ammonia and glutamate biosynthesis involves glutamate synthase (EC: which transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate. 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+.

This describes a family in several archaeal and deeply branched bacterial lineages of a homotetrameric form of the NADPH-dependent or NADH-dependent glutamate synthase (EC: and EC: respectively) small subunit. There is no corresponding large subunit.

GO terms

Biological Process

GO:0006537 glutamate biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.