Family

Efflux pump membrane protein (IPR005694)

Short name: Efflux_pump_mem

Overlapping homologous superfamilies

None.

Family relationships

Description

This family of efflux pump membrane proteins includes EmrA and EmrK [PMID: 12501312]. The EmrAB transporter confer resistance to carbonylcyanide m-chlorophenylhydrazone, nalidixic acid, and a number of other toxic compounds [PMID: 7730261]. EmrA is predicted to have a short N-terminal cytoplasmic domain, a single transmembrane helix, and a large periplasmic domain [PMID: 12482849].

GO terms

Biological Process

GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane

Molecular Function

GO:0042910 xenobiotic transmembrane transporter activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs