Family

TMEM33/Pom33 family (IPR005344)

Short name: TMEM33/Pom33

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents the TMEM33/Pom33 family. Budding yeast Pom33 is a transmembrane nucleoporin that contributes to proper distribution and/or efficient assembly of nuclear pores [PMID: 20498018]. Proteins in this entry also include Tts1 from fission yeasts [PMID: 20434336], Kr-h2 (krueppel homologue 2) from flies [PMID: 10816971] and TMEM33 from vertebrates [PMID: 25612671].

Tts1 is required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator [PMID: 20434336].

Kr-h2 is a member of the dosage-dependent hierarchy effective upon white gene expression [PMID: 10816971].

TMEM33 regulates the tubular structure of endoplasmic reticulum by suppressing the membrane-shaping activity of reticulons [PMID: 25612671].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam