Pathways & interactions
Calcium/proton exchanger (IPR004713)
Short name: CaH_exchang
Overlapping homologous superfamilies
- Calcium/proton exchanger (IPR004713)
- Calcium/proton exchanger CAX (IPR004798)
Proteins of the Ca2+:Cation Antiporter (CaCA) family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria. All of the characterised animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The Escherichia coli ChaA protein catalyses Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterised members of the family catalyze Ca2+:H+ exchange.
- TIGR00846 (caca2)