Tricarboxylate/iron carrier (IPR004686)

Short name: Mtc

Overlapping homologous superfamilies


Family relationships


The MTC family consists of a limited number of homologues, all from eukaryotes. One member of the family has been functionally characterised as a tricarboxylate carrier from rat liver mitochondria. The rat liver mitochondrial tricarboxylate carrier has been reported to transport citrate, cis-aconitate, threo-D-isocitrate, D- and L-tartrate, malate, succinate and phosphoenolpyruvate. It presumably functions by a proton symport mechanism. The rest of the characterised proteins appear to be sideroflexins involved in iron transport.

GO terms

Biological Process

GO:0006811 ion transport
GO:0055085 transmembrane transport

Molecular Function

GO:0015075 ion transmembrane transporter activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.