Iroquois-class homeodomain protein (IPR003893)

Short name: Iroquois_homeo

Overlapping homologous superfamilies


Domain relationships



This is a motif found only in Iroquois-class homeodomain proteins. It has unknown function. Examples include iroquois-class homeodomain protein IRX-4, and homeobox proteins caupolican and araucan, which control proneural and vein forming genesand are positive transcriptional controllers of achaete-scute. They may act as activators that interact with the transcriptional initiation complex assembled on the achaete and scute promoters.

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.