Acyl-CoA thioesterase (IPR003703)

Short name: Acyl_CoA_thio

Overlapping homologous superfamilies

Family relationships



Acyl-CoA thioesterases are a group of enzymes that catalyse the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH). They consequently have the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. They may also be involved in the metabolic regulation of peroxisome proliferation.

This family includes acyl-CoA thioesterase 2 [PMID: 1645722], acyl-coenzyme A thioesterase 8 [PMID: 15194431] and peroxisomal long-chain acyl-CoA thioesterase 1 [PMID: 10092594].

GO terms

Biological Process

GO:0006637 acyl-CoA metabolic process

Molecular Function

GO:0047617 acyl-CoA hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.