Pointed domain (IPR003118)

Short name: Pointed_dom

Overlapping homologous superfamilies

Domain relationships


The highly conserved PNT (or Pointed) domain is found within a subset of the Ets transcription factors, including mammalian Ets-1, Ets-2, Erg, Fli-1, GABPalpha, and Tel, as well as Drosophila Pnt-P2 and Yan. The PNT domain is structurally related to the larger group of SAM domains through a common tertiary arrangement of four alpha-helices. A role in protein-protein association has been established for the PNT domain [PMID: 10828014, PMID: 15351649].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0043565 sequence-specific DNA binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles