Family

6-hydroxymethylpterin diphosphokinase MptE-like (IPR002826)

Short name: MptE-like

Overlapping homologous superfamilies

None.

Family relationships

Description

The archaeal members of this family are known to represent a 6-hydroxymethylpterin diphosphokinase (6-HMDPK), known as MptE, which catalyses the formation of 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) from 6-HMD and ATP [PMID: 22931285]. 6-HMDP is the precursor of the pterin containing moiety of the essential C1-carriers tetrahydrofolate and tetrahydromethanopterin. The family also includes a number of uncharacterised proteins from bacteria.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER