Holo-[acyl carrier protein] synthase (IPR002582)

Short name: ACPS

Overlapping homologous superfamilies

Family relationships


Holo-acyl carrier protein synthase (ACPS) transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to Ser-36 of acyl carrier protein (ACP) in Escherichia coli. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of the cysteamine thiol of 4'-PP [PMID: 7559576]. In eukaryotes such as the yeast Neosartorya fumigata, ACPS is mitochondrial [PMID: 21195204].

GO terms

Biological Process

GO:0006633 fatty acid biosynthetic process

Molecular Function

GO:0008897 holo-[acyl-carrier-protein] synthase activity
GO:0000287 magnesium ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.