Binding Site

Biotin-binding site (IPR001882)

Short name: Biotin_BS


Biotin, which plays a catalytic role in some carboxyl transfer reactions, is covalently attached, via an amide bond, to a lysine residue in enzymes requiring this coenzyme [PMID: 2673009, PMID: 2896195, PMID: 6438443, PMID: 1526981]. Sequence data reveal that the region around the biocytin (biotin-lysine) residue is well conserved and is evolutionary related to that around the lipoyl-binding lysine residue of 2-oxo acid dehydrogenase acyltransferases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns