Sec1-like protein (IPR001619)

Short name: Sec1-like

Overlapping homologous superfamilies

Family relationships


Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [PMID: 8769846]. They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion [PMID: 10903948].

GO terms

Biological Process

GO:0006904 vesicle docking involved in exocytosis
GO:0016192 vesicle-mediated transport

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.