Domain

Flavivirus non-structural protein NS4B (IPR001528)

Short name: Flavi_NS4B

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

Flaviviruses encode a single polyprotein. This is cleaved into three structural and seven non-structural proteins. The NS4B protein is small and poorly conserved among the Flaviviruses. NS4B contains multiple hydrophobic potential membrane spanning regions [PMID: 2174669]. NS4B may form membrane components of the viral replication complex and could be involved in membrane localisation of NS3 and NS5 (see IPR000208) [PMID: 2174669].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam