Domain

Type II/IV secretion system protein (IPR001482)

Short name: T2SS/T4SS

Overlapping homologous superfamilies

Domain relationships

None.

Description

This entry contains both type II and type IV pathway secretion proteins from bacteria. Proteins in this entry include VirB11 ATPase (P07169), which is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection [PMID: 11566978].

The type II protein secretion system (T2SS) is a sophisticated multi-protein machinery containing 12-15 different proteins [PMID: 28264910]. Historically, this system was described as the main terminal branch (MTB) of the general secretory pathway (GSP), but this nomenclature is now on obsolete [PMID: 15223057].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PROSITE patterns