Domain

Flavivirus capsid protein C (IPR001122)

Short name: Flavi_capsidC

Overlapping homologous superfamilies

Domain relationships

None.

Description

Flaviruses are small, enveloped RNA viruses that use arthropods such as mosquitoes for transmission to their vertebrate hosts, and include Yellow fever virus, West Nile virus, Tick-borne encephalitis virus, Japanese encephalitis virus, and Dengue virus 2 [PMID: 15378043]. Flaviviruses consist of three structural proteins: the core nucleocapsid protein C, and the envelope glycoproteins M (IPR000069) and E. The virion of these viruses is a nucleocapsid covered by a lipoprotein envelope, where the nucleocapsid is a complex of capsid protein C and mRNA. The capsid protein C is a dimeric alpha-helical protein, and its interaction with RNA is critical for the production of viable virus particles [PMID: 12768036].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005198 structural molecule activity

Cellular Component

GO:0019028 viral capsid

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam