Flavivirus non-structural protein NS2A (IPR000752)

Short name: Flavi_NS2A

Overlapping homologous superfamilies


Domain relationships



NS2A is a hydrophobic protein about 25kDa in size, which is cleaved from NS1 by a membrane bound host protease [PMID: 7474145]. NS2A has been found to associate with the dsRNA within the vesicle packages. It has also been found that NS2A associates with the known replicase components and so NS2A has been postulated to be part of this replicase complex [PMID: 9636360].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003725 double-stranded RNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.