Hepatitis C virus non-structural protein NS4a (IPR000745)

Short name: HCV_NS4a

Overlapping homologous superfamilies


Domain relationships



NS4a (non-structural protein) forms an integral part of the NS3 serine protease in Hepatitis C virus, as it is required in a number of cases as a cofactor of cleavage [PMID: 9568891, PMID: 9261364]. It has also been reported that NS4a interacts with NS4b and NS3 to form a multi-subunit replicase complex [PMID: 9261364].

GO terms

Biological Process

GO:0016032 viral process

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0019012 virion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.