Elongation factor EFG, domain V-like (IPR000640)

Short name: EFG_V-like

Overlapping homologous superfamilies

Domain relationships


Elongation factor 2 (EF2 or EFG) is folded into five domains, with domains I and II forming the N-terminal block, domains IV and V forming the C-terminal block, and domain III providing the covalently-linked flexible connection between the two [PMID: 11054294]. This entry represents the domain V of EF2 of both prokaryotes and eukaryotes (also known as eEF2). This domain is also found in elongation factor 4 and some tetracycline resistance proteins and adopts a ferredoxin-like fold [PMID: 12471894].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.