UbiA prenyltransferase family (IPR000537)

Short name: UbiA_prenyltransferase

Overlapping homologous superfamilies


Family relationships


The UbiA family of prenyltransferases includes bacterial 4-hydroxybenzoate octaprenyltransferase (gene ubiA); yeast mitochondrial para-hydroxybenzoate--polyprenyltransferase (gene COQ2); protohaem IX farnesyltransferase (haem O synthase) from yeast and mammals (gene COX10), and from bacteria (genes cyoE or ctaB) [PMID: 8155731, PMID: 7885224]; and 2-acylphloroglucinol 4-prenyltransferase and 2-acyl-4-prenylphloroglucinol 6-prenyltransferase from plant chloroplasts which catalyze prenylation steps in the beta-bitter acid pathway [PMID: 22166201, PMID: 25564559]. These are integral membrane proteins, which probably contain seven transmembrane segments. Archaeal family members include lycopene elongase - this type of enzyme has been shown to be involved in bacterioruberin synthesis in Halobacterium salinarum and Haloferax volcanii [PMID: 21840984].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.