{"metadata":{"accession":"G3SNH9","id":"G3SNH9_LOXAF","source_organism":{"taxId":"9785","scientificName":"Loxodonta africana","fullName":"Loxodonta africana (African elephant)"},"name":"Pterin-4-alpha-carbinolamine dehydratase","description":["Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription"],"length":104,"sequence":"QAGKAHRLSAEERDQLLPNLRAVGWNEVEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT","proteome":"UP000007646","gene":"PCBD1","go_terms":[{"identifier":"GO:0008124","name":"4-alpha-hydroxytetrahydrobiopterin dehydratase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006729","name":"tetrahydrobiopterin biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"e369d4a6ba0e4ec491088fa090c6667d92b80728","counters":{"domain_architectures":17300,"entries":10,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"cdd":1,"panther":1,"ncbifam":2,"hamap":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":17300}}}