{"metadata":{"accession":"D3GWN7","id":"D3GWN7_ECO44","source_organism":{"taxId":"216592","scientificName":"Escherichia coli O44:H18 (strain 042 / EAEC)","fullName":"Escherichia coli O44:H18 (strain 042 / EAEC)"},"name":"G/U mismatch-specific DNA glycosylase","description":["Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells"],"length":168,"sequence":"MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR","proteome":null,"gene":"mug","go_terms":[{"identifier":"GO:0000700","name":"mismatch base pair DNA N-glycosylase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006285","name":"base-excision repair, AP site formation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"6d3eb109c1e174cd82c598bd72ab8f3ce4283767","counters":{"domain_architectures":69726,"entries":11,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"ssf":1,"pfam":1,"hamap":1,"ncbifam":1,"panther":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":69726}}}