{"metadata":{"accession":"P45381","id":"ACY2_HUMAN","source_organism":{"taxId":"9606","scientificName":"Homo sapiens","fullName":"Homo sapiens (Human)"},"name":"Aspartoacylase","description":["Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids"],"length":313,"sequence":"MTSCHIAEEHIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKKCTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVGPQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIAAIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLNAKSIRCCLH","proteome":"UP000005640","gene":"ASPA","go_terms":[{"identifier":"GO:0016788","name":"hydrolase activity, acting on ester bonds","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016811","name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"b4d280380897cbd59ff40da1da8545ff27d11c17","counters":{"domain_architectures":3919,"entries":14,"isoforms":0,"proteomes":1,"sets":3,"structures":8,"taxa":1,"dbEntries":{"ssf":1,"pfam":2,"cdd":1,"cathgene3d":2,"pirsf":1,"panther":1,"hamap":1,"ncbifam":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":3919}}}