{"metadata":{"accession":"W8RNX8","id":"W8RNX8_9RHOB","source_organism":{"taxId":"1294273","scientificName":"Roseicyclus elongatus DSM 19469","fullName":"Roseicyclus elongatus DSM 19469"},"name":"Flavin-dependent thymidylate synthase","description":["Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant"],"length":301,"sequence":"MPLTDDQLAEIEAARATPQPTLRAVAPGMEQHLYKAVPVLDHGFVRVIDYMGDDAAIVQAARVSYGAGTKKTRDDSGLIRYLMRHWHSTPFEMCEIKLHVKLPVFVARQWIRHRTANVNEYSARYSILDREFYIPEPDALAAQSTVNNQGRGEVLQGEEAARVLEILKSDAGRAYNNYEAMLSQDGQQGLARELARMNLPANIYTQWYWKVDLHNLFHFLRLRADEHAQYEIRVYAQAIADMVKDWVPAAYGAFEDYRMGGVALSAKGVEVLKRRLAGEDVTQENSGMSKGEWREFVEVFG","proteome":"UP000019593","gene":"thyX","go_terms":[{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050797","name":"thymidylate synthase (FAD) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006231","name":"dTMP biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"04840fd37d530bca727bb00ea092349a854c8917","counters":{"domain_architectures":9312,"entries":10,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"cdd":1,"hamap":1,"panther":1,"ncbifam":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":9312}}}