{"metadata":{"accession":"U6CQT0","id":"U6CQT0_NEOVI","source_organism":{"taxId":"452646","scientificName":"Neovison vison","fullName":"Neovison vison (American mink)"},"name":"Lipoyl amidotransferase LIPT1, mitochondrial","description":["Lipoyl amidotransferase that catalyzes the transfer of lipoyl moieties from lipoyl-protein H of the glycine cleavage system (lipoyl-GCSH) to E2 subunits of the pyruvate dehydrogenase complex (PDCE2). Unable to catalyze the transfer of octanoyl from octanoyl-GCSH to PDCE2. In vitro, it is also able to catalyze the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes but this reaction may not be physiologically relevant"],"length":373,"sequence":"MLIPFSMKNCFQLLCNCKVPAAGFKNKVKSGLIFQSVSSDIYQNLAVEDWIHDHVNLEGKPVLFLWRNSPSVVIGRHQNPWQECNLNLMREEGVKLARRRSGGGTVYHDMGNINLTFFTTKKKYDRMQNLKLVVRALKAVQPQLDIQATKRCDLLLDGQFKISGTASKIGRTTAYHHCTLLCSTDRTSLSSLLKSPYQGIRSNATASIPSIVKNLLEKDPTLTCEVLMNAIAAEYAAYHQIDNHINLINPTDETLFPGINNKARELQTWEWIYGKTPKFSINTSFNVLYEQSHLEIKIFIDIKDGRIEICNIEAPNHWLPLEICDKLNSSFIGSKFCPNEITMLTNILHRTCPEDDELHNRWNILCEKIKGIM","proteome":null,"gene":"LIPT","go_terms":[{"identifier":"GO:0036211","name":"protein modification process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0009249","name":"protein lipoylation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c31ed954e7a430bfa6effa7d5abb1606810f26b8","counters":{"domain_architectures":40137,"entries":11,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"cdd":1,"ssf":1,"pfam":1,"profile":1,"panther":1,"ncbifam":1,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":40137}}}