{"metadata":{"accession":"S9WEK2","id":"S9WEK2_CAMFR","source_organism":{"taxId":"419612","scientificName":"Camelus ferus","fullName":"Camelus ferus (Wild bactrian camel)"},"name":"Type-2 angiotensin II receptor","description":["Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation"],"length":362,"sequence":"MKDNFTLATISKNITSSLHVGHVNISGNESTFNCSHKPSDKHLDAIPVLYYIIFVVGFLVNTIVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCINPFLYCFVGNRFQQKLRRVFRVPITWLQGKRESVSCRKSSSLREMETFVS","proteome":"UP000694856","gene":"AGTR2","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004945","name":"angiotensin type II receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006954","name":"inflammatory response","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0042981","name":"regulation of apoptotic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0097746","name":"blood vessel diameter maintenance","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":394800,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"profile":1,"pfam":1,"panther":1,"prosite":1,"prints":3,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":394800}}}