{"metadata":{"accession":"R9NVP9","id":"R9NVP9_PSEHS","source_organism":{"taxId":"1305764","scientificName":"Pseudozyma hubeiensis (strain SY62)","fullName":"Pseudozyma hubeiensis (strain SY62) (Yeast)"},"name":"Inosine triphosphate pyrophosphatase","description":["Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions","Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions"],"length":193,"sequence":"MSKPTLTFVTGNANKLREVKQIFALSPDFPYELTNKDLDLPEIQGTTRDVAQAKCAAAAKALGGACITEDTALGFHALGGLPGPYIKDFMKTIGHDGLNKMLDGFEDRSASAICTFAYCAGPGEQVQLFEGKTEGIIVPPRGPTHFGWDPILEIKNTGLTYAEMDPKYKNTLSHRYKALALLQEYLVSLADKS","proteome":"UP000014071","gene":"PHSY_000103","go_terms":[{"identifier":"GO:0047429","name":"nucleoside triphosphate diphosphatase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009143","name":"nucleoside triphosphate catabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"029a777975285995c6aff1e90978714c8929fb21","counters":{"domain_architectures":32111,"entries":10,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"cdd":1,"hamap":1,"panther":1,"ncbifam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":32111}}}